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ABCD of Drug Development

Recent Projects

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Recent projects at QSCL

Development of inhaled pharmaceuticals:

  • consultancy and Ethics Committee work address both preclinical & clinical development
  • regulatory testing strategies based on decades of experience in toxicology & metabolism using both the general & inhalation routes
  • selection & management of EU CROs for toxicology and bioanalytical programmes
  • recent projects on inhaled generics, diabetes, sexual dysfunction, and nasal toxicity and & anatomy

Development of excipients and technologies for new inhalation formulations:

  • these projects related to UK & USA submissions for new technologies for inhalation therapy
  • monitoring of literature includes regulatory affairs & conferences on inhaled powders and devices
  • recent projects on several excipient candidates for inhalation formulations

Gene therapy:

  • programme of preclinical evaluation of a vector for pulmonary administration

Lung metabolism:

  • the effects of pulmonary p450 on toxicity were used to select candidate pesticides

Information services:

  • projects in this area related to diabetes, nasal toxicity and anatomy, to pulmonary metabolism, and particularly to new iIhalation excipients and formulation technologies
  • we are available for due diligence investigations and evaluation of novel commercial technologies
  • 0ur database of over 2000 international contacts is available to support your research and development
  • extensive experience in selection of contract laboratories; including specialist services in inhalation pharmacology & efficacy, and evaluation of preclinical QT prolongation

Scientific meetings:

  • attendance at scientific meetings each quarter to update my customers on recent developments
  • recent presentations include lectures on nasal anatomy, preclinical toxicology, and First-time-in-Man
  • on-site training modules can also be provided - please let us know of your interests. Enhanced computer systems and formal teaching qualifications facilitate high-quality individual presentations